Know more

Our use of cookies

Cookies are a set of data stored on a user’s device when the user browses a web site. The data is in a file containing an ID number, the name of the server which deposited it and, in some cases, an expiry date. We use cookies to record information about your visit, language of preference, and other parameters on the site in order to optimise your next visit and make the site even more useful to you.

To improve your experience, we use cookies to store certain browsing information and provide secure navigation, and to collect statistics with a view to improve the site’s features. For a complete list of the cookies we use, download “Ghostery”, a free plug-in for browsers which can detect, and, in some cases, block cookies.

Ghostery is available here for free: https://www.ghostery.com/fr/products/

You can also visit the CNIL web site for instructions on how to configure your browser to manage cookie storage on your device.

In the case of third-party advertising cookies, you can also visit the following site: http://www.youronlinechoices.com/fr/controler-ses-cookies/, offered by digital advertising professionals within the European Digital Advertising Alliance (EDAA). From the site, you can deny or accept the cookies used by advertising professionals who are members.

It is also possible to block certain third-party cookies directly via publishers:

Cookie type

Means of blocking

Analytical and performance cookies

Realytics
Google Analytics
Spoteffects
Optimizely

Targeted advertising cookies

DoubleClick
Mediarithmics

The following types of cookies may be used on our websites:

Mandatory cookies

Functional cookies

Social media and advertising cookies

These cookies are needed to ensure the proper functioning of the site and cannot be disabled. They help ensure a secure connection and the basic availability of our website.

These cookies allow us to analyse site use in order to measure and optimise performance. They allow us to store your sign-in information and display the different components of our website in a more coherent way.

These cookies are used by advertising agencies such as Google and by social media sites such as LinkedIn and Facebook. Among other things, they allow pages to be shared on social media, the posting of comments, and the publication (on our site or elsewhere) of ads that reflect your centres of interest.

Our EZPublish content management system (CMS) uses CAS and PHP session cookies and the New Relic cookie for monitoring purposes (IP, response times).

These cookies are deleted at the end of the browsing session (when you log off or close your browser window)

Our EZPublish content management system (CMS) uses the XiTi cookie to measure traffic. Our service provider is AT Internet. This company stores data (IPs, date and time of access, length of the visit and pages viewed) for six months.

Our EZPublish content management system (CMS) does not use this type of cookie.

For more information about the cookies we use, contact INRA’s Data Protection Officer by email at cil-dpo@inra.fr or by post at:

INRA
24, chemin de Borde Rouge –Auzeville – CS52627
31326 Castanet Tolosan CEDEX - France

Dernière mise à jour : Mai 2018

Menu Logo Principal UB AgroSup CNRS

Home

TRICETOX

TRICETOXContaminants et Environnements : Santé, Adaptabilité, Comportements et Usages (CESA) 2013

Environmental impact of synthetic and natural ß-triketone herbicides: detection, microbial adaptation, biodegradation and toxicity.

Most agricultural production relies on the use of chemicals to maintain high crop yields. The use of these chemicals in farming practices is viewed as an integral part of the success of the intensive farming. However, most of the pesticides applied to agricultural lands may affect non-target organisms and contaminate soil and water media. Increasing public concern about the impact of pesticides on the environment, and European legislation has led to develop some strategies to evaluate and to prevent the potential impacts of different land management practices.
In this context, new generations of less environmentally dangerous molecules, such as lower impact pesticides, biopesticides and natural product-based pesticides have been introduced. Despite this, a lot of work has to be carried out concerning several aspects of the development of these news substances and particularly to evaluate the possible risks and adverse effects of such compounds on environment and humans.
The TRICETOX project focuses on studying the ß-triketone herbicide family, a post-emergence maize selective herbicides belonging to this new generation of molecules which have been introduced on the market, in replacement of atrazine, banned in several European countries in 2003. Inside this family, four compounds will be studied in detail, two synthetic ones, i.e. sulcotrione and mesotrione and two natural ones i.e. leptospermome and myrigalone.
The TRICETOX project aims precisely to answer the following questions:
(1) How to develop analytical tools suitable for a high capacity monitoring of the ß-triketone herbicides in the framework of environmental risk assessment?
(2) What are the microbial genes coding for the catabolic enzymes involved in the bacterial biodegradation of ß-triketone herbicides? Are these genes regulated and how?
(3) Is ß-triketone biodegradation enough for their dissipation in the environment? Are those microorganisms and/or enzymes suitable for a potential bioremediation solution?
(4) Are the natural ß-triketone herbicides a safe alternative to synthetic ones?
The objectives of this project are: (i) to develop bioassays and biosensors as innovative and low cost analytical tools for the detection of the ß-triketone herbicides. (ii) to characterize the genetic system involved in the synthetic ß-triketone herbicide degradation pathways of the sulcotrione degrading strain Pseudomonas putida 1OP, and the mesotrione degrading strain Bacillus sp. 3B6. (iii) to focus on the natural ?-triketone herbicides by addressing their soil behaviour, by studying their impact on soil microbial communities with microcosm studies, by studying their biodegradation pathways and by testing the toxicity of these compounds and their degradation products. (iv) to communicate to scientific and general public, to contribute to higher education program, and to promote results towards industrial partners.
This innovating project will search for gaining new insights about the global environmental impact of the triketone herbicides, towards multidisciplinary scientific approaches, bringing together specialists from complementary disciplinary areas (microbial ecologists, biochemists, analytical chemists, and molecular biologists).
From an academic point of view, the expected results of this study will help in a better understanding of the fate and behaviour of those pesticides, and on the relevance of the natural triketone herbicides compared to their synthetic counterparts. The obtained results will undoubtedly lead to improving current knowledge and state-of-the-art in genetic characterisation of bacterial adaptation mechanisms, and to develop analytical innovative and competitive tools, suitable for environmental risk assessment.

Partners

AgroEcolgy INRA
 
 ICCF Institut de Chimie de Clermont-Ferrand
 
 UPVD-IMAGES Institut de Modélisation et d'Analyses en Environnement et Santé
 
 UPVD-LCBE Laboratoire de Chimie des Biomolécules et de l’Environnement
 
 LMGE Laboratoire Microorganismes: Genome et Environnement
 
 USDA Natural Products Utilization Research unit

ANR grant: 410 000 euros
 Beginning and duration: septembre 2013 - 48 mois

 

ANR Programme: Contaminants et Environnements : Santé, Adaptabilité, Comportements et Usages (CESA) 2013

Project ID: ANR-13-CESA-0002

Project coordinator:
Lise BARTHELMEBS (Institut de Modélisation et d'Analyses en Environnement et Santé)
barthelm@univ-perp.fr

Scientific Manager UMR Agroécologie : Fabrice MARTIN-LAURENT